Tag Archives: inhaled steroids

ASTHMA DURING PREGNANCY: EXACERBATIONS, MANAGEMENT, AND HEALTH OUTCOMES FOR MOTHER AND INFANT

FCAAIA Notes: In pregnancy, about 1/3 of mothers with asthma get worse, 1/3 get better, and 1/3 remain the same.  The pattern tends to be the same from one pregnancy to the next.  The control often improves in the last … Continue reading

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REVISITING THE SAFETY OF LABAS IN CHILDREN WITH SEVERE ASTHMA

FCAAIA Notes: Twenty years ago the SMART study suggested a risk of long-acting beta agonists (LABA) use, However, the rail was associated with the use of LABA alone and NOT with the concurrent use of inhaled corticosteroids (ICS). Study after … Continue reading

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SERIOUS ASTHMA EVENTS WITH BUDESONIDE PLUS FORMOTEROL VS. BUDESONIDE ALONE and ARE LONG-ACTING BETA-AGONISTS SAFE TO ADD TO TREATMENT REGIMENS FOR ASTHMA IN CHILDREN?

FCAAIA Notes: A little bad press can go a long way and can be hard to overcome even with a lot of good press. The long-acting beta agonists (long-acting cousins of albuterol, LABAs) are available with low dose inhaled in … Continue reading

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INHALED CORTICOSTEROIDS SAFE, EFFECTIVE, BUT SYSTEMIC COMPLICATION CONCERNS REMAIN

FCAAIA Notes: Inhaled corticosteroids (ICS) are the treatment of choice for persistent asthma as defined in every guideline or practice parameter EVER published (the first was published nearly 25 years ago).  Over the years, numerous studies reported potential of side … Continue reading

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APPROPRIATE USE OF PRESSURIZED METERED-DOSE INHALERS FOR ASTHMA

FCAAIA Notes: No medication can give its best benefit if not taken properly.  The same holds true for metered dose inhalers for asthma. If your inhaler does not help when you use it, maybe your technique is a little off. … Continue reading

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PERCENTAGE OF PARTICIPANTS HAVE ASTHMA EXACERBATIONS UP TO 2 YEARS AFTER DECREASING CONTROLLER MEDICATIONS

FCAAIA Notes: The National Asthma Education and Prevention Program published its first set of guidelines for the diagnosis and management of asthma nearly 25 years ago. There have been several revisions since. However, all iterations of the Guidelines identify patients … Continue reading

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UNCONTROLLED ASTHMA LINKED WITH NEGATIVE ICS BELIEFS IN URBAN COHORT

FCAAIA Notes: There is so much research regarding the safety of asthma medications and the risks of poorly controlled asthma that it never fails to amaze me that some patients are still more afraid of the treatment than the disease. … Continue reading

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PEDIATRIC CORTICOSTEROIDS HAVE MINIMAL EFFECT ON ADULT HEIGHT

FCAAIA Notes: Are you a glass is half-full or half-empty type of person? Your answer might change the way you interpret this study.  The “half-empty” person might look at this and say, “OMG!!! Children with asthma who were treated long-term … Continue reading

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IS LOW DOSE INHALED CORTICOSTEROID THERAPY AS EFFECTIVE FOR INFLAMMATION AND REMODELING IN ASTHMA?

FCAAIA NOTES:  Inhaled corticosteroids (ICS) are the preventive treatment of choice for persistent asthma. Over the years, there have been numerous studies showing that higher doses do not necessarily work better than lower doses.  Those studies recommend adding a second preventive … Continue reading

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DOES BODY MASS INDEX INFLUENCE RESPONSIVENESS TO INHALED CORTICOSTEROIDS IN PERSISTENT ASTHMA?

FCAAIA Notes: As you read the abstract below, you should know that FeNO is a marker of bronchial inflammation, the underlying physiologic problem in asthma. Inhaled corticosteroids, decrease the inflammation, lower the FeNO, and help control asthma symptoms. No other … Continue reading

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