FCAAIA Notes: Itch is sometimes but not always from allergy. Histamine released from certain cells in the skin is one cause of itch. In those cases, antihistamines might be useful symptoms relievers. When itch is from allergy, topical or oral steroids might be helpful.
But what about itch from other causes? For instance, molecules released from nerve endings (“neurotransmitters”) can also trigger “neurogenic” itch that will not respond to antihistamines or steroids. In those cases, topical capsaicin might help. Capsaicin is the molecule in chili peppers that gives them their heat. When used on the skin Continue reading “ANTIPRURITIC EFFECT OF PRETREATMENT WITH TOPICAL CAPSAICIN 8% ON HISTAMINE- AND COWHAGE-EVOKED ITCH IN HEALTHY VOLUNTEERS”