Tag: Oral immunotherapy

ALLERGEN IMMUNOTHERAPY: AN UPDATED REVIEW OF SAFETY

FCAAIA Notes: The four broad categories of treatment for allergic rhinitis are avoidance of triggers, symptom reliever (rescue) medications, controller (preventive) medications, and allergen immunotherapy.  Only immunotherapy can “cure” the disease by changing the way your immune system recognizes and responds to the triggers of your nasal allergies.

Immunotherapy can be administered by injections (subcutaneous, “SCIT”) or under the tongue (sublingual “SLIT”).  Although many practitioners offer SLIT for all allergens as drops, SLIT is only available and FDA approved for grass and ragweed. Dust mite SLIT has been approved but is not commercially available yet.

Although there are not many well-controlled studies, SCIT is more effective than SLIT for pollen immunotherapy and Continue reading “ALLERGEN IMMUNOTHERAPY: AN UPDATED REVIEW OF SAFETY”

AAAAI: ORAL IMMUNOTHERAPY FOR GLUTEN ALLERGY PASSES TEST BUT QUESTIONS REMAIN ON SAFETY, EFFECTIVENESS

FCAAIA Notes: If you have been following this blog over the years (or search it now), you know that I have posted many articles about oral immunotherapy (OIT) to food.  This study looked at the feasibility of OIT to wheat.  The researchers found that desensitization to wheat is possible.  However, only about ½-2/3 of the study participants tolerated a dose of about 4.4 grams (about 1 ½ slices of bread. More were able to tolerate larger amounts than before the study.

The flip side of this success is the high reaction rate.  More than 10% had mostly mild reactions.  So we have to ask, how many had accidental ingestions with symptoms after their diagnosis but before they entered the study? Continue reading “AAAAI: ORAL IMMUNOTHERAPY FOR GLUTEN ALLERGY PASSES TEST BUT QUESTIONS REMAIN ON SAFETY, EFFECTIVENESS”

SKIN PATCH SAFE, MODESTLY EFFECTIVE FOR PEANUT ALLERGY

FCAAIA Notes: Epicutaneous immunotherapy (EPIT) has been under study for peanut desensitization for quite some time.  It is still a long way from market. EPIT appears effective in protecting peanut allergic patients from small accidental ingestions.  Some patients even tolerated very high doses in challenge.  But, in comparison to oral peanut immunotherapy (OIT) Continue reading “SKIN PATCH SAFE, MODESTLY EFFECTIVE FOR PEANUT ALLERGY”

ORAL IMMUNOTHERAPY FOR EGG ALLERGY

FCAAIA Notes: I have written about food oral immunotherapy (OIT) many times in this column.  This is another study indicating that OIT to food, in this case egg, is not 100% effective, is not a permanent cure if not continued in those who tolerate it, and is not 100% safe. Fortunately a great majority of children allergic to egg can eventually tolerate it in baked products, making avoidance a little less of a burden. Continue reading “ORAL IMMUNOTHERAPY FOR EGG ALLERGY”

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